Chemical Structure : Torcetrapib
CAS No.:
262352-17-0
Torcetrapib
(CP-529414, CP529414)
Catalog No. : PC-42892Not For Human Use, Lab Use Only.
Torcetrapib (CP-529414) is a potent cholesteryl ester transfer protein (CETP) inhibitor with IC50 of 37 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4289201
Biological Activity
Torcetrapib (CP-529414) is a potent cholesteryl ester transfer protein (CETP) inhibitor with IC50 of 37 nM.
Physicochemical Properties
M.Wt
600.4733
Formula
C26H25F9N2O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-
References
1. Maeda K, et al. Bioorg Med Chem Lett.
2. Brousseau ME, et al. N Engl J Med.
3. Clark RW, et al. Arterioscler Thromb Vasc Biol.
4. Lloyd DB, et al. J Biol Chem.
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