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Treprostinil

Chemical Structure : Treprostinil

CAS No.: 81846-19-7

Treprostinil (UT-15)

Catalog No.: PC-25367Not For Human Use, Lab Use Only.

Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 of 0.6 nM and 6.2 nM, respectively, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 of 0.6 nM and 6.2 nM, respectively, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration. 

Physicochemical Properties

M.Wt 390.52
Formula C23H34O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetic acid

References

1. Tian Y, et al. J Cell Mol Med. 2025 Sep;29(17):e70815.

2. Whittle BJ, et al. Biochem Pharmacol. 2012 Jul 1;84(1):68-75.

3. Ghonem N, et al. Am J Transplant. 2011 Nov;11(11):2508-16.

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