TrkA inhibitor V1

Chemical Structure : TrkA inhibitor V1

Catalog No.: PC-20475Not For Human Use, Lab Use Only.

TrkA inhibitor V1 is an isoform-selective inhibitor of TrkA kinase with IC50 of 199 nM, 470-fold selectivity over TrkB.

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Biological Activity

TrkA inhibitor V1 is an isoform-selective inhibitor of TrkA kinase with IC50 of 199 nM, 470-fold selectivity over TrkB.

M.Wt	524.62
Formula	C31H32N4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[[4-Amino-3-(4-cyclohexyl-1-piperazinyl)-9,10-dihydro-9,10-dioxo-1-anthracenyl]amino]benzoic acid

1. Noritaka Furuya, et al. Bioorg Med Chem Lett. 2020 Jan 1;30(1):126775.