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Tubercidin

Chemical Structure : Tubercidin

CAS No.: 69-33-0

Tubercidin (Sparsomycin A;7-Deazaadenosine;NSC-56408)

Catalog No.: PC-42061Not For Human Use, Lab Use Only.

An antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity.

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Biological Activity

An antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity; incorporates into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis; also exhibits antifungal and antiviral activities.

Physicochemical Properties

M.Wt 266.2533
Formula C11H14N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-β-D-ribofuranosyl-

References

1. Mooberry SL, et al. Cancer Lett. 1995 Sep 25;96(2):261-6.

2. Olsen DB, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3944-53.

3. Drew ME, et al. J Biol Chem. 2003 Nov 21;278(47):46596-600.

4. Aoki JI, et al. Parasitol Res. 2009 Jan;104(2):223-8.

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