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U7D-1

Chemical Structure : U7D-1

CAS No.:

U7D-1

Catalog No.: PC-38903Not For Human Use, Lab Use Only.

U7D-1 is a selective USP7-degrading Proteolysis Targeting Chimera (PROTAC). U7D-1 showed selective and effective USP7 degradation, and maintained potent cell growth inhibition in p53 mutant cancer cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

U7D-1 is a selective USP7-degrading Proteolysis Targeting Chimera (PROTAC). U7D-1 showed selective and effective USP7 degradation, and maintained potent cell growth inhibition in p53 mutant cancer cells.

Physicochemical Properties

M.Wt 940.159
Formula C53H65N9O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. Yuan Pei, et al. Angew Chem Int Ed Engl. 2022 Jun 12. doi: 10.1002/anie.202204395.

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