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UAMC-3203

Chemical Structure : UAMC-3203

CAS No.: 2271358-65-5

UAMC-3203 (UAMC3203)

Catalog No.: PC-35743Not For Human Use, Lab Use Only.

UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1.
UAMC-3203 shows an improved protection compared to Fer-1 against multi-organ injury in mice.
UAMC-3203 epresents novel lead compounds with therapeutic potential in relevant ferroptosis-driven disease models.

Physicochemical Properties

M.Wt 508.122
Formula C25H38ClN5O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(benzylamino)-4-(cyclohexylamino)-N-(2-(piperazin-1-yl)ethyl)benzenesulfonamide hydrochloride

References

1. Devisscher L, et al. J Med Chem. 2018 Oct 25. doi: 10.1021/acs.jmedchem.8b01299.

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