Chemical Structure : UAMC-3203
CAS No.: 2271358-65-5
Catalog No.: PC-35743Not For Human Use, Lab Use Only.
UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1.
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UAMC-3203 is a novel potent, drug-like ferroptosis inhibitor with IC50 of 12 nM, inhibit erastin-induced ferroptotic cell death more potently than Ferrostatin-1.
UAMC-3203 shows an improved protection compared to Fer-1 against multi-organ injury in mice.
UAMC-3203 epresents novel lead compounds with therapeutic potential in relevant ferroptosis-driven disease models.
M.Wt | 508.122 | |
Formula | C25H38ClN5O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-(benzylamino)-4-(cyclohexylamino)-N-(2-(piperazin-1-yl)ethyl)benzenesulfonamide hydrochloride |
1. Devisscher L, et al. J Med Chem. 2018 Oct 25. doi: 10.1021/acs.jmedchem.8b01299.
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