Chemical Structure : UCB-5307
CAS No.: 1515887-44-1
Catalog No.: PC-49445Not For Human Use, Lab Use Only.
UCB-5307 is a small molecule compound inhibiting TNFR1 signalling and downstream function in vitro, bind directly to TNF with slow binding kinetics (KD= 6 nM).
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UCB-5307 is a small molecule compound inhibiting TNFR1 signalling and downstream function in vitro, bind directly to TNF with slow binding kinetics (KD= 6 nM).
M.Wt | 343.42 | |
Formula | C22H21N3O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-[(2,5-Dimethylphenyl)methyl]-α-4-pyridinyl-1H-benzimidazole-2-methanol |
1. James O'Connell, et al. Nat Commun. 2019 Dec 19;10(1):5795.
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