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UCM05

Chemical Structure : UCM05

CAS No.: 1094451-90-7

UCM05 (G28UCM)

Catalog No.: PC-25151Not For Human Use, Lab Use Only.

UCM05 is a specfic small molecule inhibitor of bacterial cell division targeting the GTP-binding site of FtsZ with Kb of 43 uM, inhibits the growth of the Gram-positive bacterium B. subtilis with MIC of 100 uM, also is a fatty acid synthase (FASN) inhibitor wiht activity against HER2+ breast cancer.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

UCM05 is a specfic small molecule inhibitor of bacterial cell division targeting the GTP-binding site of FtsZ with Kb of 43 uM, inhibits the growth of the Gram-positive bacterium B. subtilis with MIC of 100 uM, also is a fatty acid synthase (FASN) inhibitor wiht activity against HER2+ breast cancer.

Physicochemical Properties

M.Wt 464.38
Formula C24H16O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

naphthalene-1,3-diyl bis(3,4,5-trihydroxybenzoate)

References

1. Ruiz-Avila LB, et al. ACS Chem Biol. 2013 Sep 20;8(9):2072-83.

2. Li S, et al. Virol J. 2025 Jul 19;22(1):249.

3. Teresa Puig, et al. Breast Cancer Res. 2011;13(6):R131.

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