Chemical Structure : UCP1172
Catalog No.: PC-27159Not For Human Use, Lab Use Only.
UCP1172 is an antibacterial dihydrofolate reductase (DHFR) inhibitor with IC50 of 8.9 nM, 220 nM, 410 nM and 30 nM for S. aureus DfrB (wt SaDHFR), DfrG, DfrA and DfrK, inhibits MRSA isolates with MIC50 of 0.625 ug/mL for UCH MRSA 1 (dfrG).
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UCP1172 is an antibacterial dihydrofolate reductase (DHFR) inhibitor with IC50 of 8.9 nM, 220 nM, 410 nM and 30 nM for S. aureus DfrB (wt SaDHFR), DfrG, DfrA and DfrK, inhibits MRSA isolates with MIC50 of 0.625 ug/mL for UCH MRSA 1 (dfrG).
| M.Wt | 416.48 | |
| Formula | C24H24N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Reeve SM, et al. Cell Chem Biol. 2016;23(12):1458-1467.

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