Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : UCPH-102
Catalog No.: PC-62149Not For Human Use, Lab Use Only.
UCPH-102 is a selective, brain penetrant inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 420 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
UCPH-102 is a selective, brain penetrant inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 420 nM.
UCPH-102 exhibits no inhibitory activity aganist EAAT2-5 (>300 uM).
UCPH-102 has been shown to cross the blood-brain barrier, and become a valuable tool for studying the role of EAAT1 in brain.
| M.Wt | 330.387 | |
| Formula | C21H18N2O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Huynh TH, et al. Bioorg Med Chem. 2012 Dec 1;20(23):6831-9.
2. Haym I, et al. ChemMedChem. 2016 Feb 17;11(4):403-19.
3. Erichsen MN, et al. Neurochem Res. 2014 Oct;39(10):1964-79.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
