Chemical Structure : UHMCP1
CAS No.: 2103079-87-2
Catalog No.: PC-72029Not For Human Use, Lab Use Only.
UHMCP1 is a small molecule that prevents the SF3b155/U2AF65 interaction, binds to the hydrophobic pocket of the U2AF65 UHM domain (Kd=1-20 uM), impacts splicing and cell viability.
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UHMCP1 is a small molecule that prevents the SF3b155/U2AF65 interaction, binds to the hydrophobic pocket of the U2AF65 UHM domain (Kd=1-20 uM), impacts splicing and cell viability.
| M.Wt | 297.446 | |
| Formula | C19H27N3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(1R,5S)-3-(4-(1H-indol-3-yl)butan-2-yl)-3-azabicyclo[3.2.1]octan-8-amine |
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1. Asaki Kobayashi, et al. FEBS J. 2022 Feb;289(3):682-698.

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