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UK-78282 hydrochloride

Chemical Structure : UK-78282 hydrochloride

CAS No.: 136647-02-4

UK-78282 hydrochloride (UK-78,282, UK78282 )

Catalog No.: PC-28189Not For Human Use, Lab Use Only.

UK-78282 hydrochloride is a selective inhibitor of Kv1.3 voltage-gated potassium channel with IC50 of 200 nM, shows preferentially blocking and binding to the C-type inactivated state of the channel, displays marked selectivity for Kv1.3 over other closely related K+ channels.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

UK-78282 hydrochloride is a selective inhibitor of Kv1.3 voltage-gated potassium channel with IC50 of 200 nM, shows preferentially blocking and binding to the C-type inactivated state of the channel, displays marked selectivity for Kv1.3 over other closely related K+ channels.

Physicochemical Properties

M.Wt 466.06
Formula C29H36ClNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((Benzhydryloxy)methyl)-1-(3-(4-methoxyphenyl)propyl)piperidine hydrochloride

References

1. Hanson DC, et al. Br J Pharmacol. 1999 Apr;126(8):1707-16.

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