UM-232 | STING inhibitor | Probechem Biochemicals

Chemical Structure : UM-232

Catalog No.: PC-27260Not For Human Use, Lab Use Only.

UM-232 is a selecitve, next-generation, covalent STING inhibitor wth EC50 of 2.6 uM in THP1 R232 cells, inhibits STING oligomerization.

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Biological Activity

UM-232 is a selecitve, next-generation, covalent STING inhibitor wth EC50 of 2.6 uM in THP1 R232 cells, inhibits STING oligomerization.

M.Wt	535.09
Formula	C29H35ClN6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((S)-4-(4-([1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)-5-oxo-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pentyl)-2-chloropropanimidamide

1. Barasa L, et al. ACS Med Chem Lett. 2026 Jun 19;17(7):1547-1554.