Catalog No.: PC-21831Not For Human Use, Lab Use Only.
UMM-766 is an orally available nucleoside analog with potent, broad-spectrum antiviral activity against multiple members of orthopoxviruses (EC50<1 uM against VACV).
UMM-766 is an orally available nucleoside analog with potent, broad-spectrum antiviral activity against multiple members of orthopoxviruses (EC50<1 uM against VACV).
UMM-766 has relatively less effective against CPXV having EC50 of 2.17 and 8.09 µM in RAW and MRC5 cells, respectively.
UMM-766 (oral 10 mg/kg) protected mice against disease in the semi-lethal VACV murine model.
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2. Mudhasani RR, et al. Microbiol Spectr. 2024 Feb 23:e0358623.
