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Chemical Structure : UNC2250
CAS No.: 1493694-70-4
Catalog No.: PC-72371Not For Human Use, Lab Use Only.
UNC2250 is a potent, selective Mer inhibitor with IC50 of 1.7 nM, displays >100-fold selectivity over Axland Tyro3.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | $528 | In stock | |
| 1 g | Get quote |
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UNC2250 is a potent, selective Mer inhibitor with IC50 of 1.7 nM, displays >100-fold selectivity over Axland Tyro3.
UNC2250 inhibits Mer phosphorylation in 697 B-ALL cells with IC50 of 9.8 nM.
UNC2250 inhibits colony formation in soft agar cultures of the BT-12 rhabdoid tumor and the Colo699 NSCLC cell lines.
UNC2250 also displays high selectivity on a broad survey of kinase families.
| M.Wt | 440.592 | |
| Formula | C24H36N6O2 | |
| Appearance | Solid | |
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1. Zhang W, et al. J Med Chem. 2013 Dec 12;56(23):9683-92.
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