UNC2541 | Mer inhibitor | Probechem Biochemicals

Chemical Structure : UNC2541

CAS No.: 1612782-86-1

UNC2541 (UNC-2541)

Catalog No.: PC-23043Not For Human Use, Lab Use Only.

UNC2541 is a potent, specific Mer tyrosine kinase (MerTK) inhibitor with IC50 of 4.4 nM, >25-fold selective over Tyro3, Axl, and FLT3, shows EC50 of 550 nM in pMerTK ELISA assays.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$218	In stock
50 mg	$358	In stock
100 mg		Get quote

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Biological Activity

UNC2541 is a potent, specific Mer tyrosine kinase (MerTK) inhibitor with IC50 of 4.4 nM, >25-fold selective over Tyro3, Axl, and FLT3, shows EC50 of 550 nM in pMerTK ELISA assays.

Physicochemical Properties

M.Wt	471.58
Formula	C24H34FN7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-7-Amino-N-(4-fluorobenzyl)-8-oxo-2,9,16,18,21-pentaazabicyclo[15.3.1]henicosa-1(20),16,18-triene-20-carboxamide

References

1. Andrew L McIver, et al. ChemMedChem. 2017 Feb 3;12(3):207-213.

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UNC2541 (UNC-2541)

Biological Activity

Physicochemical Properties

References

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