UPF1854 |CAS:1569869-46-0 Probechem Biochemicals

Chemical Structure : UPF1854

UPF1854 (UPF 1854;UPF-1854)

Catalog No.: PC-63335Not For Human Use, Lab Use Only.

UPF1854 is a potent tankyrase inhibitor with IC50 of 12 nM and 200 nM for TNKS1 and TNKS-2 respectively, displays no cross-reactivity versus other PARP proteins.

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Biological Activity

UPF1854 is a potent tankyrase inhibitor with IC50 of 12 nM and 200 nM for TNKS1 and TNKS-2 respectively, displays no cross-reactivity versus other PARP proteins.
UPF1854 displays good long-term growth inhibition in DLD-1 cancer cells.

Physicochemical Properties

M.Wt	269.308
Formula	C14H15N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[2-(6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-ylamino)-ethyl]-phenol

References

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UPF1854 (UPF 1854;UPF-1854)

Biological Activity

Physicochemical Properties

References

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