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UPF 648

Chemical Structure : UPF 648

CAS No.: 213400-34-1

UPF 648 (UPF-648, UPF648)

Catalog No.: PC-24007Not For Human Use, Lab Use Only.

UPF 648 (UPF-648) is a potent, selective kynurenine 3-hydroxylase (KMO) inhibitor, increases the kynurenine and kynurenic acid concentration in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

UPF 648 (UPF-648) is a potent, selective kynurenine 3-hydroxylase (KMO) inhibitor, increases the kynurenine and kynurenic acid concentration in vitro and in vivo.

Physicochemical Properties

M.Wt 259.08
Formula C11H8Cl2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1S,2S)-2-(3,4-dichlorobenzoyl)cyclopropanecarboxylic acid

References

1. Sapko MT, et al. Exp Neurol. 2006 Jan;197(1):31-40.

2. Amori L, et al. J Neurochem. 2009 Apr;109(2):316-25.

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