UR-PI376 |CAS:1192559-94-6 Probechem Biochemicals

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Chemical Structure : UR-PI376

UR-PI376 (UR PI376)

Catalog No.: PC-63422Not For Human Use, Lab Use Only.

UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R.

Physicochemical Properties

M.Wt	342.465
Formula	C17H22N6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-cyano-1-[4-(1H-imidazol-4-yl)butyl]-3-[(2-phenylthio)ethyl]guanidine

References

1. Igel P, et al. J Med Chem. 2009 Oct 22;52(20):6297-313.

2. Reher TM, et al. Biochem Pharmacol. 2012 Jul 15;84(2):192-203.

3. Gschwandtner M, et al. Br J Pharmacol. 2013 Sep;170(1):136-43.

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UR-PI376 (UR PI376)

Biological Activity

Physicochemical Properties

References

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