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UTAinh-B3

Chemical Structure : UTAinh-B3

CAS No.: 306279-85-6

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UTAinh-B3 (ATB3)

Catalog No.: PC-26599Not For Human Use, Lab Use Only.

UTAinh-B3 (ATB3) is a selective competitive inhibitor of urea transporter UT-A2 with IC50 of 6.38 uM, shows 6-fold stronger inhibition potency toward UT-B.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UTAinh-B3 (ATB3) is a selective competitive inhibitor of urea transporter UT-A2 with IC50 of 6.38 uM, shows 6-fold stronger inhibition potency toward UT-B.

Physicochemical Properties

M.Wt 264.30
Formula C12H12N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Amino-5-[(2,3-dimethoxyphenyl)methylene]-4(5H)-thiazolone

References

1. Shen-Ming Huang, et al. Nat Commun. 2024 Nov 26;15(1):10226.

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