UTAinh-F11 | UT-A inhibitor | Probechem Biochemicals

Chemical Structure : UTAinh-F11

UTAinh-F11 (UT-A inhibitor CF11)

Catalog No.: PC-26598Not For Human Use, Lab Use Only.

UTAinh-F11 (UT-A inhibitor CF11) is a selective uncompetitive inhibitor of urea transporter UT-A with IC50 of 2.78 uM for hUT-A2, has 10 times selectivity for UT-A1 than UT-B.

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Biological Activity

UTAinh-F11 (UT-A inhibitor CF11) is a selective uncompetitive inhibitor of urea transporter UT-A with IC50 of 2.78 uM for hUT-A2, has 10 times selectivity for UT-A1 than UT-B.

Physicochemical Properties

M.Wt	430.92
Formula	C17H19ClN2O5S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-chloro-3-(1,1-dioxidoisothiazolidin-2-yl)phenyl)-2-methoxy-5-methylbenzenesulfonamide

References

1. Shen-Ming Huang, et al. Nat Commun. 2024 Nov 26;15(1):10226.

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UTAinh-F11 (UT-A inhibitor CF11)

Biological Activity

Physicochemical Properties

References

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