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Chemical Structure : UTBinh-14
Catalog No.: PC-21373Not For Human Use, Lab Use Only.
UTBinh-14 is a potent, highly selective inhibitor for urea transporter UT-B with IC50 of 11 nM, with over a thousand-fold selectivity over UT-A.
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UTBinh-14 is a potent, highly selective inhibitor for urea transporter UT-B with IC50 of 11 nM, with over a thousand-fold selectivity over UT-A.
UTBinh-14 selectively and reversibly inhibited urea transport with IC50 of 25.1 nM and reduced urinary concentration in mice.
| M.Wt | 455.57 | |
| Formula | C20H17N5O2S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. M. O. Anderson, et al. J. Med. Chem. 55, 5942–5950 (2012).
2. Chi G, et al. Sci Adv. 2023 Sep 29;9(39):eadg8229.
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