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Chemical Structure : UTKO1
Catalog No.: PC-23288Not For Human Use, Lab Use Only.
UTKO1 is a cell migration inhibitor targeting 14-3-3ζ, also is a selective small molecule inhibitor of notochord tubulogenesis, binds directly and selectively to Ciona 14-3-3εa.
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UTKO1 is a cell migration inhibitor targeting 14-3-3ζ, also is a selective small molecule inhibitor of notochord tubulogenesis, binds directly and selectively to Ciona 14-3-3εa.
UTKO1 inhibits 14-3-3εa interacting and colocalizing with its binding partner ezrin/radixin/moesin (ERM).
UTKO1 inhibits tumor cell migration by targeting 14-3-3ζ.
UTKO1 inhibits the second EGF-induced wave of Rac1 activation.
| M.Wt | 374.52 | |
| Formula | C23H34O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mizotani Y, et al. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8873-E8881.
2. Sawada M, et al. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1385-9.
3. Kobayashi H, et al. J Biol Chem. 2011 Nov 11;286(45):39259-68.
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