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UTL-5g

Chemical Structure : UTL-5g

CAS No.: 646530-37-2

UTL-5g (GBL-5g)

Catalog No.: PC-61792Not For Human Use, Lab Use Only.

UTL-5g (GBL-5g) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UTL-5g (GBL-5g) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity; lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice; a novel chemo- and radioprotective agent.

Physicochemical Properties

M.Wt 271.097
Formula C11H8Cl2N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2,4-dichlorophenyl)-5-methylisoxazole-3-carboxamide

References

1. Shaw J, et al. J Exp Ther Oncol. 2011;9(2):129-37.

2. Shaw J, et al. Cancer Chemother Pharmacol. 2013 Sep;72(3):703-7.

3. Carruthers NJ, et al. Eur J Pharmacol. 2017 Sep 15;811:66-73.

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