UW-MD-95

Chemical Structure : UW-MD-95

Catalog No.: PC-22544Not For Human Use, Lab Use Only.

UW‐MD‐95 is a potent pseudo‐irreversible butyrylcholinesterase (BChE) inhibitor with IC50 of 60 nM, does not inhibit AChE, shows potent neuroprotective in the Aβ25‐35 model of AD.

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Biological Activity

UW‐MD‐95 is a potent pseudo‐irreversible butyrylcholinesterase (BChE) inhibitor with IC50 of 60 nM, does not inhibit AChE, shows potent neuroprotective in the Aβ25‐35 model of AD.

Physicochemical Properties

M.Wt	407.56
Formula	C25H33N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	13-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[1,2-b]quinazolin-10-yl heptylcarbamate

References

1. Allison Carles, et al. CNS Neurosci Ther. 2024 Jun;30(6):e14814.

2. Darras FH, et al. ACS Med Chem Lett. 2012;3:914‐919.

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UW-MD-95

Biological Activity

Physicochemical Properties

References

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