Chemical Structure : Umibecestat
CAS No.: 1387560-01-1
Catalog No.: PC-60085Not For Human Use, Lab Use Only.
Umibecestat (CNP520) is a potent, selective, and efficacious β-Secretase (BACE1) inhibitor with IC50 of 11 nM and 30 nM for BACE1 and BACE2, respectively.
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|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
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| M.Wt | 513.801 | |
| Formula | C19H15ClF7N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(6-((3R,6R)-5-amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl)-5-fluoropyridin-2-yl)-3-chloro-5-(trifluoromethyl)picolinamide |
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1. Neumann U, et al. EMBO Mol Med. 2018 Sep 17. pii: e9316. doi: 10.15252/emmm.201809316.

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