Urelumab
(Anti-human CD137-hIgG4P mAb, human IgG4P-Kappa)
Catalog No.: PC-Ab1012Not For Human Use, Lab Use Only.
Urelumab is an agonist antibody to CD137 with potential application as an immuno-oncology therapeutic, enhances NK-cell activation increasing CD25 expression and IFNɣ production, but not in vitro ADCC. Urelumab enhances T-cell and natural killer-cell antitumor activity in preclinical models, and may enhance cytotoxic activity of rituximab..
Urelumab is an agonist antibody to CD137 with potential application as an immuno-oncology therapeutic, enhances NK-cell activation increasing CD25 expression and IFNɣ production, but not in vitro ADCC. Urelumab enhances T-cell and natural killer-cell antitumor activity in preclinical models, and may enhance cytotoxic activity of rituximab.
Physicochemical Properties
M.Wt
Formula
Human IgG4P-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
