Urotensin-II receptor antagonist-1

Chemical Structure : Urotensin-II receptor antagonist-1

Catalog No.: PC-28277Not For Human Use, Lab Use Only.

Urotensin-II receptor antagonist-1 is a potent, selective human Urotensin II receptor antagonist with Ki of 16 nM on HEK293 cells expressing recombinant human UT receptor.

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Biological Activity

Urotensin-II receptor antagonist-1 is a potent, selective human Urotensin II receptor antagonist with Ki of 16 nM on HEK293 cells expressing recombinant human UT receptor.

Physicochemical Properties

M.Wt	460.44
Formula	C25H31Cl2N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanone, 2-[(3,4-dichlorophenyl)methylamino]-1-[(2R,3R)-3-phenyl-2-(1-pyrrolidinylmethyl)-1-piperidinyl]-, rel-

References

1. McAtee JJ, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3500-3.

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