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Utomilumab

Chemical Structure : Utomilumab

CAS No.:

Utomilumab (Anti-human CD137-hIgG2 mAb, human IgG2-Lambda 2; PF-05082566)

Catalog No.: PC-Ab1040Not For Human Use, Lab Use Only.

Utomilumab (PF-05082566) is a ligand-blocking antibody, binds 4-1BB between CRDs 3 and 4, a fully human monoclonal antibody (mAb) agonist that selectively binds to 4-1BB (also called CD137), a protein receptor expressed in many cancer-fighting T cells. Utomilumab (PF-05082566) binds specifically to 4-1BB (CD-137), a receptor protein found in many immune cells, such as T-cells (killer T-cells and helper T-cells) and natural killer cells..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Utomilumab (PF-05082566) is a ligand-blocking antibody, binds 4-1BB between CRDs 3 and 4, a fully human monoclonal antibody (mAb) agonist that selectively binds to 4-1BB (also called CD137), a protein receptor expressed in many cancer-fighting T cells. Utomilumab (PF-05082566) binds specifically to 4-1BB (CD-137), a receptor protein found in many immune cells, such as T-cells (killer T-cells and helper T-cells) and natural killer cells.

Physicochemical Properties

M.Wt
Formula Human IgG2-Lambda 2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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