Catalog No.: PC-20967Not For Human Use, Lab Use Only.
VAL-083 (Dianhydrodulcitol) is a small alkylating molecule that induces interstrand DNA crosslinking, induces persistent DNA double-strand breaks (DSB) and cell-cycle arrest in a p53-dependent or p53-independent manner.
VAL-083 (Dianhydrodulcitol) is a small alkylating molecule that induces interstrand DNA crosslinking, induces persistent DNA double-strand breaks (DSB) and cell-cycle arrest in a p53-dependent or p53-independent manner.
Physicochemical Properties
M.Wt
146.14
Formula
C6H10O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
O[C@H]([C@H](O)[C@@]1(CO1)[H])[C@]2(CO2)[H]
References
1. Jiménez-Alcázar M, et al. Mol Cancer Ther. 2021 Jun;20(6):1029-1038.
2. Golebiewska A, et al. Acta Neuropathol. 2020 Dec;140(6):919-949.
3. Nemeth L, et al. Cancer Chemother Rep 1972;56:593–602.
