VCP979 | p38 MAPK inhibitor | Probechem Biochemicals

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Chemical Structure : VCP979

VCP979 (VCP-979)

Catalog No.: PC-49694Not For Human Use, Lab Use Only.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VCP979 (VCP-979) is a novel selective small molecule p38 MAPK inhibitor with a significantly greater affinity for the active form of p38 MAPK, has significant anti-fibrotic effects in vitro and in vivo.
VCP979 significantly promoted axonal/white matter (WM) remodeling, neural progenitor cell migration, and improved functional recovery in T2DM mice.
VCP979 improved axonal/WM remodeling and functional outcomes in a diabetic mouse stroke mode.
VCP979 effectively suppressed orthotopic pancreatic cancer growth and metastasis.
VCP979 effectively reduced renal fibrosis, extracellular matrix accumulation, and alleviated epithelial-mesenchymal transition in UUO rats.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

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VCP979 (VCP-979)

Biological Activity

Physicochemical Properties

References

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