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Chemical Structure : VDAC inhibitor SC18
Catalog No.: PC-38524Not For Human Use, Lab Use Only.
VDAC inhibitor SC18 is a specific small molecule targeting the NADH-binding pocket of voltage dependent anion channels (VDAC), decreases mitochondrial membrane potential ΔΨm in HepG2 cells (EC50=25 uM), modulates mitochondrial metabolism in cancer cells, inhibit cell proliferation and induce cell death.
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VDAC inhibitor SC18 is a specific small molecule targeting the NADH-binding pocket of voltage dependent anion channels (VDAC), decreases mitochondrial membrane potential ΔΨm in HepG2 cells (EC50=25 uM), modulates mitochondrial metabolism in cancer cells, inhibit cell proliferation and induce cell death.
| M.Wt | 385.683 | |
| Formula | C15H7ClF3N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Heslop KA, et al. Biomed Pharmacother. 2022 Apr 18;150:112928.
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