VDR 4-1 |CAS:303203-28-3 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-Vitamin D Receptor (VDR)-VDR 4-1

Chemical Structure : VDR 4-1

VDR 4-1

Catalog No.: PC-61773Not For Human Use, Lab Use Only.

VDR 4-1 is a novel non-steroidal, small-molecule agonist of vitamin D receptor (VDR).

Packing	Price	Stock	Quantity
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VDR 4-1 is a novel non-steroidal, small-molecule agonist of vitamin D receptor (VDR); demonstrates potent transcriptional activities in a VDR reporter gene assay, and significantly ameliorates cardiac hypertrophy in cell culture and in animal models; also effectively suppresses secondary hyperparathyroidism in 1α-hydroxylase knockout mice; does not induce hypercalcemia at high doses in contrast to naturally occurring VDR agonist (1,25-D3 or calcitriol).

Physicochemical Properties

M.Wt	512.061
Formula	C28H30ClNO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(ethylthio)ethyl 7-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

References

1. Khedkar SA, et al. Sci Rep. 2017 Aug 16;7(1):8427.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

VDR 4-1

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.