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VHL-alkyne

Chemical Structure : VHL-alkyne

CAS No.:

VHL-alkyne

Catalog No.: PC-35014Not For Human Use, Lab Use Only.

VHL-alkyne is a VHL ligand for PROTAC synthesis..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VHL-alkyne is a VHL ligand for PROTAC synthesis.

Physicochemical Properties

M.Wt 540.679
Formula C28H36N4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,4R)-1-((S)-3,3-dimethyl-2-(3-(prop-2-yn-1-yloxy)propanamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

References

1. Savitski MM, et al. Cell. 2018 Mar 22;173(1):260-274.e25.

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