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VHL Ligand 4

Chemical Structure : VHL Ligand 4

CAS No.: 1631137-45-5

VHL Ligand 4

Catalog No.: PC-60118Not For Human Use, Lab Use Only.

A VHL ligand for PROTAC..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A VHL ligand for PROTAC.

Physicochemical Properties

M.Wt 677.861
Formula C36H47N5O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

tert-butyl ((S)-1-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

References

1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.

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