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VP1.15

Chemical Structure : VP1.15

CAS No.: 1337960-51-6

VP1.15

Catalog No.: PC-23485Not For Human Use, Lab Use Only.

VP1.15 is a potent, dual PDE7/GSK-3 inhibitor with IC50 of 1.1 (PDE7) and 1.95 uM (GSK-3), shows antipsychotic and cognitive capacities.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VP1.15 is a potent, dual PDE7/GSK-3 inhibitor with IC50 of 1.1 (PDE7) and 1.95 uM (GSK-3), shows antipsychotic and cognitive capacities.

Physicochemical Properties

M.Wt 378.29
Formula C16H16BrN3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(2,3-Diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)amino]ethanol hydrobromide

References

1. Lipina TV, et al. Neuropharmacology. 2013 Jan;64:205-14.

2. Paterniti I, et al. PLoS One. 2011 Jan 31;6(1):e15937.

3. Medina-Rodríguez EM, et al. Sci Rep. 2017 Mar 3;7:43545.

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