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Chemical Structure : VPC-80051
CAS No.: 877969-69-2 (Racemate)
Catalog No.: PC-36117Not For Human Use, Lab Use Only.
VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $168 | In stock | |
| 25 mg | $268 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1.
VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line, reduces AR-V7 mRNA levels.
| M.Wt | 301.297 | |
| Formula | C16H13F2N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-N-(1-(3,4-difluorophenyl)ethyl)-2H-indazole-3-carboxamide |
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1. Carabet LA, et al. Molecules. 2019 Feb 20;24(4). pii: E763.
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