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VPS34 inhibitor 5

Chemical Structure : VPS34 inhibitor 5

CAS No.: 2770104-92-0

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VPS34 inhibitor 5

Catalog No.: PC-20375Not For Human Use, Lab Use Only.

VPS34 inhibitor 5 is a potent, selective, and orally bioavailable VPS34 inhibitor with IC50 of 83 nM, >95-fold selectivity over other PIK family kinases.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    VPS34 inhibitor 5 is a potent, selective, and orally bioavailable VPS34 inhibitor with IC50 of 83 nM, >95-fold selectivity over other PIK family kinases.

    Physicochemical Properties

    M.Wt 276.34
    Formula C14H20N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (5aS,8aR)-2-((R)-3-methylmorpholino)-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one

    References

    1. Dennis X Hu, et al. J Med Chem. 2022 Sep 8;65(17):11500-11512.

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