Chemical Structure : VT-1161
CAS No.:
1340593-59-0
VT-1161
(Oteseconazole, VT1161)
Catalog No. : PC-61753Not For Human Use, Lab Use Only.
VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6175301
Biological Activity
VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
Physicochemical Properties
M.Wt
527.403
Formula
C23H16F7N5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol
References
1. Hoekstra WJ, et al. Bioorg Med Chem Lett.
2. Warrilow AG, et al. Antimicrob Agents Chemother.
3. Garvey EP, et al. Antimicrob Agents Chemother.
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