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VU 0038882

Chemical Structure : VU 0038882

CAS No.: 429653-28-1

VU 0038882 (VU0038882)

Catalog No.: PC-70355Not For Human Use, Lab Use Only.

A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism; prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis.

Physicochemical Properties

M.Wt 276.295
Formula C17H12N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-(furan-2-yl)-1H-pyrazol-5-yl)naphthalen-1-ol

References

1. Mike LA, et al. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8206-11.

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