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Chemical Structure : VU0152099
CAS No.: 612514-42-8
Catalog No.: PC-62161Not For Human Use, Lab Use Only.
VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
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VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM.
VU0152099 shows no agonist activity but potentiates responses of M(4) to acetylcholine, and is devoid of activity at other mAChR subtypes or at a panel of other GPCRs.
VU0152099 reverses amphetamine-induced hyperlocomotion in rats.
| M.Wt | 355.412 | |
| Formula | C18H17N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethylthieno[5,4-b]pyridine-2-carboxamide |
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1. Brady AE, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):941-53.
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