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VU0155056

Chemical Structure : VU0155056

CAS No.: 1130067-18-3

VU0155056 (VU-0155056)

Catalog No.: PC-28471Not For Human Use, Lab Use Only.

VU0155056 is a potent, selective phospholipase D (PLD) inhibitor, suppresses fMLP-stimulated PLD activity with IC50 of 0.04 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU0155056 is a potent, selective phospholipase D (PLD) inhibitor, suppresses fMLP-stimulated PLD activity with IC50 of 0.04 uM.

Physicochemical Properties

M.Wt 414.51
Formula C25H26N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide

References

1. Tsai YR, et al. Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):507-19.

2. Robert Lavieri, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2240-3.

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