Chemical Structure : VU0285655-1
CAS No.: 1158347-73-9
Catalog No.: PC-72955Not For Human Use, Lab Use Only.
VU0285655-1 (BML280) is a potent, selective PLD2 inhibitor with IC50 of 90 nM, 21-fold selective over PLD1, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
VU0285655-1 (BML280) is a potent, selective PLD2 inhibitor with IC50 of 90 nM, 21-fold selective over PLD1, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells.
| M.Wt | 465.98 | |
| Formula | C25H28ClN5O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide hydrochloride |
|
1. Burkhardt U, et al. Eur J Pharmacol. 2015 Aug 15;761:398-404. 2. Robert Lavieri, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2240-3.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright