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VU0285655-1

Chemical Structure : VU0285655-1

CAS No.: 1158347-73-9

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VU0285655-1 (BML280, VU0285655)

Catalog No.: PC-72955Not For Human Use, Lab Use Only.

VU0285655-1 (BML280) is a potent, selective inhibitor of PLD2, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

VU0285655-1 (BML280) is a potent, selective inhibitor of PLD2, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells.

Physicochemical Properties

M.Wt 465.98
Formula C25H28ClN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide hydrochloride

References

1. Burkhardt U, et al. Eur J Pharmacol. 2015 Aug 15;761:398-404.

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