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Chemical Structure : VU0359595
Catalog No.: PC-72954Not For Human Use, Lab Use Only.
VU0359595 (VU 0359595) is a potent, selective phospholipase D (PLD) inhibitor with cell IC50 of 4 nM.
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VU0359595 (VU 0359595, ML-270) is a potent, selective phospholipase D1 (PLD1) inhibitor with cell IC50 of 4 nM, >1700-fold selective for PLD1 over PLD2.
| M.Wt | 497.4 | |
| Formula | C25H29BrN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Burkhardt U, et al. Neuropharmacology. 2014 Apr;79:1-9.
2. Burkhardt U, et al. Eur J Pharmacol. 2015 Aug 15;761:398-404.
3. Chaves-Moreira D, et al. J Cell Biochem. 2017 Apr;118(4):726-738.
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