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Chemical Structure : VU0415248
Catalog No.: PC-20508Not For Human Use, Lab Use Only.
VU0415248 is a highly selective antagonist of muscarinic acetylcholine receptor subtype 1 (M1 mAChR) with IC50 of 0.4 uM and 0.18 uM for hM1R and rM1R, respectively.
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VU0415248 is a highly selective antagonist of muscarinic acetylcholine receptor subtype 1 (M1 mAChR) with IC50 of 0.4 uM and 0.18 uM for hM1R and rM1R, respectively.
VU0415248 shows very high selectivity for the M1 receptor over the M2–5 subtypes across all five human and rat receptors.
| M.Wt | 425.51 | |
| Formula | C21H23N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bruce J Melancon, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1044-8.
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