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Chemical Structure : VU0466551
Catalog No.: PC-35863Not For Human Use, Lab Use Only.
VU0466551 (VU-0466551) is a potent, selective, small-molecule GIRK activator with EC50 of 70.6 nM (GIRK1/2 channels).
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VU0466551 (VU-0466551) is a potent, selective, small-molecule GIRK activator with EC50 of 70.6 nM (GIRK1/2 channels).
VU0466551 demonstrates analgesic effects when dosed alone or in combination with sub-maximally effective doses of morphine.
| M.Wt | 342.35 | |
| Formula | C18H16F2N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Abney KK, et al. ACS Chem Neurosci. 2018 Nov 26. doi: 10.1021/acschemneuro.8b00370.
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