VU 0469381 |CAS:1062368-49-3 Probechem Biochemicals

Chemical Structure : VU 0469381

Catalog No.: PC-60770Not For Human Use, Lab Use Only.

VU 0469381 (ML347) is a potent, sellective BMP receptor ALK2 antaognist with Ki of 32 nM, with no affinity for ALK3/4/5/6.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

VU 0469381 (ML347) is a potent, sellective BMP receptor ALK2 antaognist with Ki of 32 nM, with no affinity for ALK3/4/5/6.

M.Wt	352.397
Formula	C22H16N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline

1. Engers DW, et al. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3248-52.

2. Engers DW, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

3. Tsugawa D, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):549-58.