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Chemical Structure : VU0529331
CAS No.: 1286725-49-2
Catalog No.: PC-35862Not For Human Use, Lab Use Only.
VU0529331 (VU 0529331) is the first synthetic small molecule activator of non-GIRK1-containing GIRK (non-GIRK1/X) channels with EC50 of 5.1 µM and 5.2 µM for GIRK2 and GIRK1/2 in HEK293 cells, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $498 | In stock | |
| 10 mg | $788 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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VU0529331 (VU 0529331) is the first synthetic small molecule activator of non-GIRK1-containing GIRK (non-GIRK1/X) channels with EC50 of 5.1 µM and 5.2 µM for GIRK2 and GIRK1/2 in HEK293 cells, respectively.
VU0529331 can specifically modulate the activity of GIRK1-containing GIRK channels.
| M.Wt | 384.443 | |
| Formula | C22H20N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2-(3,4-dimethylphenyl)-3-(1H-pyrrol-1-yl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl)(pyrazin-2-yl)methanone |
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1. Kozek KA, et al. ACS Chem Neurosci. 2018 Sep 13. doi: 10.1021/acschemneuro.8b00287.
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