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VU0531245

Chemical Structure : VU0531245

CAS No.: 1396749-92-0

VU0531245 (VU245)

Catalog No.: PC-23274Not For Human Use, Lab Use Only.

VU0531245 (VU245) is a potent, selective SLACK channel (KNa1.1) inhibitor, inhibits WT SLACK channels with IC50 of 2.1 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU0531245 (VU245) is a potent, selective SLACK channel (KNa1.1) inhibitor, inhibits WT SLACK channels with IC50 of 2.1 uM.

Physicochemical Properties

M.Wt 391.46
Formula C17H17N3O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(1-((2-Ethoxyphenyl)sulfonyl)azetidin-3-yl)-3-(thiophen-3-yl)-1,2,4-oxadiazole

References

1. unies AM, et al. Bioorg Med Chem. 2023 Sep 30;95:117487.

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