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VU0935685

Chemical Structure : VU0935685

CAS No.:

VU0935685 (VU 0935685)

Catalog No.: PC-21229Not For Human Use, Lab Use Only.

VU0935685 is a potent, selective inhibitor of SLACK potassium channels with IC50 of 0.32 uM in in whole-cell, voltage-clamp electrophysiology (EP) assays, demonstrates selectivity versus hERG.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU0935685 is a potent, selective inhibitor of SLACK potassium channels with IC50 of 0.32 uM in in whole-cell, voltage-clamp electrophysiology (EP) assays, demonstrates selectivity versus hERG.

Physicochemical Properties

M.Wt 424.45
Formula C21H17FN4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-Fluorophenyl)-5-(1-((2-methylquinolin-8-yl)sulfonyl)azetidin-3-yl)-1,2,4-oxadiazole

References

1. Qunies AM, et al. Bioorg Med Chem. 2023 Sep 30;95:117487.

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