VU0935685 | KNa1.1 (Slack) inhibitor | Probechem Biochemicals

Chemical Structure : VU0935685

VU0935685 (VU 0935685)

Catalog No.: PC-21229Not For Human Use, Lab Use Only.

VU0935685 is a potent, selective inhibitor of SLACK potassium channels with IC50 of 0.32 uM in in whole-cell, voltage-clamp electrophysiology (EP) assays, demonstrates selectivity versus hERG.

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Biological Activity

VU0935685 is a potent, selective inhibitor of SLACK potassium channels with IC50 of 0.32 uM in in whole-cell, voltage-clamp electrophysiology (EP) assays, demonstrates selectivity versus hERG.

Physicochemical Properties

M.Wt	424.45
Formula	C21H17FN4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-Fluorophenyl)-5-(1-((2-methylquinolin-8-yl)sulfonyl)azetidin-3-yl)-1,2,4-oxadiazole

References

1. Qunies AM, et al. Bioorg Med Chem. 2023 Sep 30;95:117487.

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VU0935685 (VU 0935685)

Biological Activity

Physicochemical Properties

References

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